The ARG1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Arg1, Arginase I, Arginase, liver, and Arginase-1. This antibody recognizes Human, Mouse, and Rat antigen. The ARG1 Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene